1/11/2024 0 Comments Ilift ghohestaniOne more BP serum sample with dermal staining did not recognize any dermal or epidermal antigen.Ĭonclusion: In case of immunofluorescent dermal staining, the precise diagnosis should be confirmed by identification of the involved antigen, since it may reveal antibodies to laminin-5 or type XVII or IV collagen, in addition to the EBA antigen. San Antonio, TX 78257 (2 other locations) Is this you Claim your profile (210) 698-6777. One sample recognized exclusively a 185-kd dermal antigen corresponding to type IV collagen. The remaining serum samples were from patients with cicatricial pemphigoid having antibodies to the α3 or β3 chains of laminin-5 (n=5) or patients with BP having antibodies to the 180-kd BP antigen (n=2). Find Reviews, Ratings, Directions, Business Hours, Contact Information and book online appointment. Alternatively, a poor correlation was found for the dermal-reacting serum samples and the diagnosis of EBA of the 19 serum samples with dermal staining on SSS, only 10 reacted with the EBA antigen. One of the best Doctors, Healthcare business at 24165 Frontage Rd 102, San Antonio TX, 78257 United States. Ghohestani, director of Texas Institute of Dermatology, patients with a history of eczema, or asthma are more prone to allergic skin reactions to face paints and makeup.Allergic reactions to the cosmetic ingredients in Halloween makeup may present with an itchy or a blistery rash. He received his medical degree from Shiraz University of Medical Sciences and. Results: Epidermal staining on SSS was highly specific for pemphigoid. Ghohestani is a dermatologist in San Antonio, Texas and is affiliated with University Health-San Antonio. Main Outcome Measures: Binding sites of serum to the epidermal and/or dermal sides of SSS were correlated with their antigenic specificities. For an appointment, please call us at 21 or email info. Patients: One hundred forty-two serum samples from patients with BP (n=98), cicatricial pemphigoid (n=23), pemphigoid gestationis (n=10), EBA (n=10), and anti- type IV collagen (n=1). Ghohestani, at the Texas Institute of Dermatology Hair Loss Clinic San Antonio offers the latest treatment options for alopecia in men and women including a new UV light treatment, LED light, PRP, follicular unit hair transplantation as well as latest laser and light technology. Setting: An immunodermatology laboratory. Objective: To determine the diagnostic value of indirect immunofluorescence on sodium chloride-split skin (SSS) in differentiating the pemphigoid group of subepidermal autoimmune bullous dermatoses, including bullous pemphigoid (BP), cicatricial pemphigoid, and pemphigoid gestationis, from epidermolysis bullosa acquisita (EBA).ĭesign: Serum samples were tested using immunofluorescence on SSS and immunoblot assay on epidermal and dermal extracts, a recombinant protein corresponding to the C-terminal end of the 230-kd BP antigen, and purified laminin-5.
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